In today’s fashion world, synthetic fabrics like polyester, nylon, and spandex are common due to their affordability and versatility. However, these fabrics come with hidden health risks that could impact your well-being. Here’s why you should consider ditching synthetic clothing in favor of natural fibers like cotton, wool, hemp, and linen.

Table of Contents
1. Skin Irritation and Allergies
Synthetic fabrics are often treated with chemicals like formaldehyde and dyes, which can trigger skin irritation, rashes, or allergic reactions. For sensitive skin or conditions like eczema, these chemicals can cause more severe discomfort. Over time, even non-allergic individuals may develop sensitivities to these materials.
One study found that textile-related contact dermatitis is increasingly common due to allergenic dyes and resin treatments (DermNet NZ) [1].
2. Poor Breathability and Bacterial Growth
Unlike natural fibers, synthetics trap moisture and heat, which can promote bacterial and fungal growth. This creates a breeding ground for body odor, acne, and infections. For athletes or anyone who sweats heavily, synthetic clothing can worsen skin issues.
A clinical study published in the Journal of Clinical and Aesthetic Dermatology confirmed that non-breathable synthetic materials can exacerbate skin issues, including acne mechanica [2].
3. Chemical Exposure from Manufacturing Additives
Synthetic fabrics are often treated with chemicals like flame retardants, antimicrobial agents, and water-repellent coatings. Many of these chemicals, including perfluorinated compounds (PFCs), have been linked to cancer, hormonal disruption, and developmental issues.
The National Institute of Environmental Health Sciences (NIEHS) has highlighted the dangers of flame retardants in consumer goods, including clothing [3].
4. Microplastic Shedding and Absorption
Every time synthetic clothing is washed, it sheds microplastics that can enter our water systems, oceans, and food chains. These microplastics have been found in human tissues, including the bloodstream and placental tissue, potentially causing inflammation and long-term health issues.
A 2021 study published in Environment International confirmed microplastics in human placental tissue, raising concerns about long-term health effects [4].
5. Heat Retention and Overheating
Synthetics trap heat, preventing the body from cooling off properly. This can lead to heat rash, exhaustion, and other heat-related illnesses, especially in warm climates or during physical activity. Natural fibers like cotton and wool, in contrast, allow better temperature regulation.
According to the Laborers’ Health & Safety Fund of North America, synthetic clothing can increase the risk of heat stress in warm working conditions [5].
6. Disrupted Sleep from Poor Temperature Regulation
Wearing synthetic fabrics to bed can disrupt your sleep due to their inability to regulate temperature effectively. This leads to night sweats and restless sleep. Natural fibers like wool and cotton help maintain a comfortable body temperature for more restful sleep.
Research in the journal Nature and Science of Sleep found that people sleeping in natural fiber bedding experienced more restful sleep compared to those using synthetics [6].
7. Endocrine Disruption from Toxic Compounds
Many synthetic fabrics contain chemicals that mimic or disrupt hormones, such as phthalates and BPA. These endocrine disruptors can affect reproductive health, metabolism, and hormone levels, with potential long-term consequences for fertility and overall health.
The NIEHS has identified several synthetic textile-related compounds as endocrine disruptors with potential long-term health consequences [7].

8. Carcinogenic Dyes and Finishes
Synthetic fabrics are often dyed with chemicals that break down into carcinogenic aromatic amines, which can be absorbed through the skin or inhaled. These toxic dyes have been linked to increased cancer risk, especially with prolonged exposure.
A 2024 study in Chemosphere flagged concerns about azo dye degradation and its cancer-causing potential during skin exposure [8].
9. Blocked Skin Detox Pathways
Synthetic clothing can block the skin’s ability to sweat effectively, hindering its natural detoxification process. This forces your liver and kidneys to work harder to eliminate toxins, which can lead to health issues over time.
Health experts from Shepherd’s Dream note that natural fibers support the body’s ability to detox through the skin, while synthetics may inhibit this process [9].
10. Static Electricity and EMF Sensitivity
Synthetic fabrics generate static electricity, which can cause discomfort and sparks when touching metal objects. There are also concerns that synthetic clothing may exacerbate sensitivity to electromagnetic fields (EMFs), although more research is needed.
Studies on textile static from Darong Tester explain that synthetic fibers generate far more static electricity than natural ones, potentially affecting people sensitive to EMFs [10].
11. Reduced Comfort and Impaired Circulation
Synthetic fabrics can feel less soft and comfortable than natural fibers. Tight synthetic garments, such as compression clothing, can restrict circulation, leading to discomfort and potentially long-term health issues like varicose veins and swelling.
Articles from Fibre2Fashion report that tight synthetic clothes can cause circulation issues and discomfort, especially in activewear and undergarments [11].
12. Heavy Metal Absorption
Some synthetic fabrics are treated with heavy metals like lead, cadmium, and arsenic, which can be absorbed through the skin. Prolonged exposure to these metals can lead to neurological and developmental issues, especially in pregnant women and children.
A review in Toxics journal confirmed that textile processing can leave behind heavy metal residues with potential for skin absorption [12].
Conclusion
The health risks associated with synthetic clothing are significant, ranging from skin irritation and hormonal disruption to long-term exposure to carcinogenic dyes and chemicals. By switching to natural fibers such as cotton, wool, hemp, and linen, you can reduce your exposure to harmful substances and enjoy better comfort, breathability, and overall health. Make the switch to natural fibers today for a healthier, more sustainable wardrobe.
Sources
- DermNet NZ. Textile Contact Dermatitis.
- JCAD Dermatology. Textile Dermatitis: Review of Skin Irritation from Clothing.
- National Institute of Environmental Health Sciences (NIEHS). Flame Retardants.
- Environment International. Assessment of Dermal Exposure to Chemicals in Clothing Materials.
- Laborers’ Health & Safety Fund of North America (LHSFNA). Synthetic Fabrics vs. Natural Fibers for Preventing Heat Stress.
- Nature and Science of Sleep. Impact of Sleepwear Fabric on Sleep Quality.
- NIEHS. Endocrine Disruptors.
- Chemosphere. Toxic Chemical Migration from Synthetic Textiles into Skin (2024).
- Shepherd’s Dream. Skin and Natural Fibers: The Healthy Sleep Connection.
- Darong Tester. All About Textile Static Electricity.
- Fibre2Fashion. Unveiling the Hidden Risks: The Side Effects of Clothing and How to Safeguard Yourself.
- Toxics Journal. Health Risks of Clothing Dyes and Finishes.